Jackie Peyton is a sharp-tongued and quick-witted nurse who is trying to survive the chaotic grind of saving lives in a hectic New York City hospital. Jackie's a woman of substance who knows how to handle it all. With a white lie here, a bent rule there, and a steady dose of pain relievers for her chronic back pain, Jackie does whatever it takes to get the job done.

Miranda Fitch?s life is a waking nightmare. The accident that ended her burgeoning acting career left her with excruciating chronic back pain, a failed marriage, and a deepening dependence on painkillers. And now, she?s on the verge of losing her job as a college theater director. Determined to put on Shakespeare?s All?s Well That Ends Well, the play that promised and cost her everything, she faces a mutinous cast hellbent on staging Macbeth instead....