When a serial killer begins terrorizing New York City, claiming his victims by tattooing cryptic messages on their skin using tattoo guns loaded with poison, Lincoln Rhyme and Amelia Sachs are drawn into the case because of its connection to the decade-old Bone Collector case.

"When a New York City construction crane mysteriously collapses, causing mass destruction and injury, Rhyme and Sachs are on the case. A political group claims responsibility for the sabotage and threatens another attack in twenty-four hours, unless its demands are met. The clock is ticking. Then a clue reveals to Rhyme that his nemesis, known as the Watchmaker, has come to town to fulfill his promise of murdering the criminalist. Now Rhyme and Sachs...

"Amelia Sachs is hot on the trail of a killer. She's chasing him through a department store in Brooklyn when an escalator malfunctions. The stairs give way, with one man horribly mangled by the gears. Sachs is forced to let her quarry escape as she jumps in to try to help save the victim. She and famed forensic detective Lincoln Rhyme soon learn, however, that the incident may not be an accident at all, but the first in a series of intentional attacks....