It's up to Otto to save the world from a renegade faction of the world's most powerful villains, known as the Disciples. And when they kidnap two of Otto's friends, things get personal.

Wing and Raven find themselves in a deadly race against time to track Otto down before the other G.L.O.V.E. assassins get to him. Their pursuit takes them to a secret facility hidden deep within the Amazon rainforest, where they face a mysterious operative even deadlier than Raven. Meanwhile back at H.I.V.E., the school's own automated defence systems turn against the pupils and staff, and there is no one there to stop it.

The Higher Institute of Villainous Education is in grave danger. It's leader, Dr. Nero, has been captured by the world's most ruthless security force. It's up to Otto to save Dr. Nero. But first Otto must escape Nero's sinister replacement and H.I.V.E. itself. Will Otto be able to break into M16 as no other villain has ever done?